AAP / AMI

Opening of 2nd call: January 2026

Objectives

The aim of this call for proposals is to provide four young scientists with the means to set up and lead a research team within a laboratory established in France.

The first call, opened in 2024, allowed the funding of three chairs.

The present and second call aims to fund a fourth chair according to the same objectives as the first call.

The chair should aim to develop research of excellence in the field of the microbiome in prevention and human health, and to enrich the national research environment and infrastructures currently being built in this field.

Applicants’ research expertise should cover at least one of the research priorities/axes of the “SAMS” Programme, and in particular those addressing the following issues:

  • Developing cutting-edge research on the host-microbiome symbiosis;
  • Identify the disruptive elements – internal to the microbiome, of environmental or dietary origin, or linked to the host itself – and explain the sequence of microbial, metabolic and immune events, etc. that cause disruption of the symbiosis and homeostasis;
  • Identify biomarkers of risk, diagnosis and prognosis, as well as predictors of treatment response and toxicity, so that they can be included in the medical arsenal for personalised care;
  • Developing new preventive and therapeutic strategies, as well as specific, controlled interventional studies, which identify and correct “defects” in the microbiome in order to improve prevention in the general population, patient management and optimise treatments;
  • Developing data science relating to the study of human holobionts (host-microbiome) at the interface of biology and medicine, and mathematics (medical computing, statistics, modelling, artificial intelligence).
Details

The Chair will run for 3.5 years maximum, with funding of up to €500k (excluding management costs).

The host laboratory must provide the selected candidate with office space and a dedicated laboratory large enough to accommodate a start-up team (approximately 50 m2), as well as access to local technology platforms.

Progress

The call for junior chair is divided into two phases: the first phase, which is selective and compulsory, consists of submitting an application to demonstrate the interest in joining the French research environment (identification of the host laboratory is not compulsory); the second phase consists of submitting the research project in collaboration with the chosen host laboratory.

Useful informations

2nd Call for Junior Chair

  • Call text: coming soon
  • Application submission platform (account creation required): coming soon
  • Contact for questions: equipe@pepr-sams.fr
  • Contact for technical issues with the submission platform: eva.dsi@inserm.fr
Calendar

1st Call for Junior Chairs: closed

2nd Call for Junior Chair

  • Phase 1 submission platform opens: January 2026
  • Phase 2 submission platform opens: coming soon
  • Junior chair begins: coming soon
List of projects funded
    • Nicolas Benech

Project title: TROPHIC – Trophic Regulation of Gut Physiology through Host-Microbiome Interactions in the Context of Malnutrition and Chemotherapy

Host laboratory: Institut de Génomique Fonctionnelle de Lyon

Funding: 500k€ over 54 months max

    • Lejla Imamovic

Project title: VIROMUNE – Illuminating the Role of Viral Dark Matter in Drug-induced Alterations of Microbiome-Immune Homeostasis

Host laboratory: Institut Cochin

Funding: 500k€ over 54 months max

    • Océane Martin

Project title: GLIOBIOTA – Investigating the Impact of the Gut Bacterial Microbiome and Dietary Factors on Glioblastoma Progression and Treatment Resistance Through the Gut-Brain Axis

Host laboratory: Institut de Biochimie et Génétique Cellulaire

Funding: 500k€ over 54 months max